4-Oxo-2,4-diphenylbutanenitrile

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2-(4-Meth­oxy­phen­yl)-4-oxo-4-phenyl­butane­nitrile

The title mol-ecule, C(17)H(15)NO(2), is twisted, the dihedral angle between the terminal benzene rings being 63.30 (6)°. In the crystal, C-H⋯O and C-H⋯N inter-actions lead to supra-molecular layers in the ab plane. These are connected along the c axis via C-H⋯π inter-actions.

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2-(4-Chloro­phen­yl)-4-oxo-4-phenyl­butane­nitrile

The title mol-ecule, C16H12ClNO, has a V-shaped conformation and the dihedral angle between the planes of the phenyl and benzene rings of 64.6 (1)°. No directional intermolecular interactions could be identified in the crystal.

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4-Oxo-2,4-diphenyl­butane­nitrile

The title mol-ecule, C(16)H(13)NO, is twisted, the dihedral angle between the terminal phenyl rings being 68.40 (6)°. In the crystal, C-H⋯O and C-H⋯N inter-actions lead to supra-molecular layers in the bc plane.

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2-(3-Nitro­phen­yl)-4-oxo-4-phenyl­butane­nitrile

The structure of the title compound, C(16)H(12)N(2)O(3), contains two aromatic rings bridged by a C(3) chain. The dihedral angle between the rings is 67.6 (1)°. No classical hydrogen bonds are not found in the crystal structure.

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rac-2-[2-(4-Fluoro­phen­yl)-2-oxo-1-phenyl­eth­yl]-4-methyl-3-oxo-N-phenyl­penta­namide

The title compound, C(26)H(24)FNO(3), is a critical inter-mediate of a selective and competitive inhibitor of the enzyme 3-hy-droxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase. Inter-molecular N-H⋯O hydrogen bonding generates a chain along [give direction] that is the dominant inter-action in the crystal packing. Inter-molecular C-H⋯O inter-actions are also observed.

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ژورنال

عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online

سال: 2012

ISSN: 1600-5368

DOI: 10.1107/s1600536812006137